Week9

Proteomics
November 24

[|Functional genomics and proteomics of the cellular osmotic stress response in 'non-model' organisms.] J Exp Biol. 2007 May;210(Pt 9):1593-601.
 * Papers to discuss:**

Toxicoproteomics - The Next Step in the Evolution of Environmental Biomarkers? Toxicological Sciences 95(1), 1-4 (2007)

Mass spectrometric profiling - A diagnostic tool in fish? Marine Environmental Research 62 (2006) S105-S108

Experimental Paper:

I know this is a long paper! If you're just getting around to reading it on Monday, focus on the methods; the discussion gets a bit long!

[|Proteomic identification and functional validation of activins and BMP-11 as candidate novel muscle mass regulators.] Mol Endocrinol. 2008 Oct 16. [Epub ahead of print]
 * Additional Papers on the Topic:**

[|Identification of quorum sensing-related regulons in Vibrio vulnificus by two-dimensional gel electrophoresis and differentially displayed reverse transcriptase PCR.] FEMS Immunol Med Microbiol. 2007 Jun;50(1):94-103.

An evaluation of the use of two-dimensional gel electrophoresis in proteomics Biomolecular Engineering 18 (2001) 195-206

A Proteomic (SELDI-TOF-MS) Approach to Estrogen Agonist Screening Toxicological Sciences 95(1), 74-81 (2007)

**[PDF]** ► [|Oxidative stress and bivalves: a proteomic approach] - [|Find UW Holdings] D Sheehan, B McDonagh - ISJ, 2008 - isj.unimo.it [|View as HTML] - [|Web Search]
 * ...** up to 70 % of ROS leading to **complication** of the **...** there is growing interest in **bivalve**
 * genomics** as a **...** Several aspects of **bivalve** biology make oxidative stress of **...**

media type="custom" key="2752791" proteomic results data starts on slide 21 1227536997
 * Application of proteomics via presentation**

[|Example of MS/MS output] from 'spot' isolated from 2-D gel.

.. [|more files] 1330534010

Some real gels... media type="google" key="5319224858182837506&hl=en&fs=true" width="400" height="326"

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